Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 14/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3805125 | 0.88 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL6053349 | 0.85 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL9980718 | 0.83 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL9980933 | 0.83 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL7445210 | 0.82 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL6053185 | 0.82 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL3788649 | 0.81 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL9980694 | 0.77 | ALDH1A1 (0.45) | CRHR1 | |
| SCHEMBL6303231 | 0.77 | CRHR1 (0.78) | CRHR1 | |
| SCHEMBL6448260 | 0.76 | CRHR1 (0.48) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149583-A2 | Combinations of corticotropin releasing factor antagonists and growth hormone secretagogues | Pfizer Products Inc. (US) | 2001-10-31 | — | — | EP | claimed |