SCHEMBL7433293

SCHEMBL7433293

NC(=O)C1=C2NCCC2CC=C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CDC7 O00311 1/20 0.33
PARP1 P09874 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7437008 0.98 CDC7 (0.33) CDC7PARP1
SCHEMBL3125735 0.90 PARP1 (0.33) CDC7PARP1
SCHEMBL1422923 0.84 ALDH1A1 (0.30)
Hydrochloric Acid SCHEMBL21410155 0.83
SCHEMBL5332473 0.67 LMNA (0.35)
SCHEMBL2333754 0.66
SCHEMBL7451061 0.61 CDC7 (0.30) CDC7
SCHEMBL3075773 0.60
SCHEMBL7263753 0.59 NNMT (0.33) CDC7
SCHEMBL6671571 0.59 GABRR1 (0.34) CDC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998002420-A1 CERTAIN FUSED PYRROLECARBOXANILIDES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 1998-01-22 WO claimed
CN-116685576-A Cysteine protease inhibitors and methods of use thereof 美商帕迪斯生物科学公司 2023-09-01 CN disclosed
EP-1210328-A1 FUSED PYRROLECARBOXAMIDES: A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 2002-06-05 EP disclosed
WO-2001016103-A1 FUSED PYRROLECARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 2001-03-08 WO disclosed