Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440403 | 0.85 | MTNR1A (0.63) | SMN1; SMN2RAB9ANPC1POLBMTNR1A | |
| SCHEMBL22570687 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL7447867 | 0.81 | RAB9A (0.60) | KMT2ALMNAHPGDRAB9ANPC1 | |
| SCHEMBL11044058 | 0.81 | HPGD (0.56) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL7913254 | 0.80 | HPGD (0.55) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL307233 | 0.79 | KMT2A (0.75) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL15148379 | 0.78 | L3MBTL1 (0.55) | SMN1; SMN2KMT2ALMNAHPGDRAB9A | |
| SCHEMBL9559962 | 0.78 | HPGD (0.54) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL920107 | 0.78 | HPGD (0.54) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL2379429 | 0.78 | RAB9A (0.55) | SMN1; SMN2KMT2ALMNANR1H4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |