Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.63 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014560 | 0.85 | MTNR1A (0.56) | MTNR1AMTNR1BCES2CES1MMP13 | |
| SCHEMBL7433393 | 0.85 | SMN1; SMN2 (0.56) | MTNR1ANPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL3846489 | 0.84 | CES2 (0.61) | MTNR1AMTNR1BCES2CES1HSD11B1 | |
| SCHEMBL1194055 | 0.84 | MMP13 (0.58) | CES2CES1MMP13NPC1RAB9A | |
| SCHEMBL10480836 | 0.83 | KDM4E (0.56) | MTNR1AMTNR1BSMN1; SMN2TSHR | |
| SCHEMBL30758862 | 0.83 | CES2 (0.69) | MTNR1AMTNR1BCES2CES1HSD11B1 | |
| SCHEMBL11248287 | 0.83 | CES2 (0.69) | MTNR1AMTNR1BCES2CES1HSD11B1 | |
| Hydrochloric Acid SCHEMBL15974464 | 0.83 | CES2 (0.59) | MTNR1AMTNR1BCES2CES1HSD11B1 | |
| Hydrochloric Acid SCHEMBL3849048 | 0.83 | CES2 (0.59) | MTNR1AMTNR1BCES2CES1HSD11B1 | |
| SCHEMBL7410028 | 0.82 | MTNR1B (0.52) | MTNR1AMTNR1BCES2CES1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | disclosed |
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |