Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442699 | 0.88 | MAPT (0.35) | MAP3K5GHSRSLC7A5MAPTCCKAR | |
| SCHEMBL7435675 | 0.86 | MAPT (0.37) | GHSRMAPTCCKARCCKBRLTA4H | |
| SCHEMBL7438488 | 0.86 | CYP2C9 (0.34) | SLC7A5MAPTDHODHLTA4HCYP2C9 | |
| SCHEMBL7441596 | 0.85 | GHSR (0.34) | GHSRSLC7A5MAPTCCKARCCKBR | |
| SCHEMBL7433678 | 0.84 | GHSR (0.37) | GHSRMAPTCCKARCCKBRLTA4H | |
| SCHEMBL7441643 | 0.84 | CCKAR (0.34) | MAP3K5GHSRSLC7A5MAPTCCKAR | |
| SCHEMBL7439595 | 0.83 | GHSR (0.36) | MAP3K5GHSRSLC7A5MAPTCCKAR | |
| SCHEMBL7441953 | 0.82 | GHSR (0.35) | MAP3K5GHSRBRD4BRD2BRD3 | |
| SCHEMBL7431147 | 0.81 | MAPT (0.40) | GHSRSLC7A5MAPTALDH1A1RAB9A | |
| SCHEMBL7433296 | 0.79 | CACNA1B (0.32) | MAP3K5GHSRMAPTCCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710153-A | INTERLEUKIN CONVERTING ENZYME INHIBITORS | ONO PHRAMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761680-A2 | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |