Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.52 |
| ▸ | CTSL | P07711 | 6/20 | 0.52 |
| ▸ | CTSK | P43235 | 8/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.48 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399913 | 1.00 | CTSS (0.52) | CTSSCTSLCTSKELANEATM | |
| SCHEMBL5704553 | 0.91 | CTSL (0.53) | CTSSCTSLCTSKELANEATM | |
| SCHEMBL7438056 | 0.90 | ELANE (0.48) | CTSSCTSLCTSKELANEATM | |
| SCHEMBL10432161 | 0.86 | CTSK (0.48) | CTSSCTSLCTSKELANEATM | |
| SCHEMBL7429948 | 0.85 | CTSS (0.46) | CTSSCTSLCTSKELANEATM | |
| SCHEMBL12906609 | 0.85 | ATM (0.61) | CTSSCTSLCTSKELANEATM | |
| SCHEMBL10432394 | 0.84 | CTSK (0.46) | CTSSCTSLCTSKELANEATM | |
| SCHEMBL7296754 | 0.84 | CTSK (0.57) | CTSSCTSLCTSKCTSB | |
| SCHEMBL10445815 | 0.83 | CTSS (0.47) | CTSSCTSLCTSKELANEATM | |
| SCHEMBL7321385 | 0.82 | TRPM8 (0.55) | CTSSCTSLCTSKCTSBCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114927-A | Hypotensive agents and inhibiting renin | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0371179-A1 | Novel analogs of peptidase substrates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0368719-A2 | Novel analogs of peptidase substrates | MERRELL PHARMACEUTICALS INC. (US) | 1990-05-16 | — | — | EP | disclosed |
| EP-0362002-A1 | HIV protease inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0356595-A1 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0275101-A2 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-07-20 | — | — | EP | disclosed |