Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371195 | 0.85 | VCAM1 (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9348382 | 0.82 | ALDH1A1 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL96634 | 0.81 | ACHE (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2725343 | 0.79 | ALDH1A1 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5163404 | 0.79 | ALDH1A1 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29066086 | 0.79 | TUBB4A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13000074 | 0.77 | ACHE (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30283027 | 0.75 | TUBB4A (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7365821 | 0.75 | TUBB4A (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2088203 | 0.75 | TUBB4A (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237929-A1 | 3,5-Disubstituted pyrocatechol derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-09-23 | — | — | EP | disclosed |