Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428126 | 0.92 | ALDH1A1 (0.48) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7437784 | 0.89 | ALDH1A1 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7447951 | 0.89 | DRD4 (0.50) | MEN1KMT2AALDH1A1DRD4MAPT | |
| SCHEMBL10995400 | 0.88 | ALDH1A1 (0.50) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7446109 | 0.87 | LMNA (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7446327 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7495736 | 0.84 | TSHR (0.49) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL7431672 | 0.84 | LMNA (0.53) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7434855 | 0.84 | LMNA (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7440410 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |