Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446109 | 0.92 | LMNA (0.49) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7434220 | 0.89 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL7431672 | 0.88 | LMNA (0.53) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7434855 | 0.88 | LMNA (0.49) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7428126 | 0.88 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL10992865 | 0.88 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7435698 | 0.88 | AIMP2 (0.48) | ALDH1A1SMN1; SMN2LMNAMAPK1GAA | |
| SCHEMBL7440410 | 0.83 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7446327 | 0.82 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL7437776 | 0.82 | LMNA (0.38) | ALDH1A1SMN1; SMN2LMNAMAPTMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |