Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434220 | 0.92 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL7446327 | 0.91 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL7436573 | 0.89 | HTT (0.47) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL7446109 | 0.89 | LMNA (0.49) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL7437784 | 0.88 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL7443888 | 0.88 | POLB (0.48) | ALDH1A1SMN1; SMN2MAPK1LMNAKDM4E | |
| SCHEMBL10992553 | 0.88 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL7431672 | 0.87 | LMNA (0.53) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL7435694 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL7434855 | 0.86 | LMNA (0.49) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |