Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 10/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432010 | 0.89 | HTR1A (0.52) | HRH3SLC6A4HTR1AEPHX2HTR2A | |
| SCHEMBL7430403 | 0.82 | SLC6A4 (0.57) | HRH3SLC6A4HTR1AKCNH2 | |
| Oxalic Acid SCHEMBL4739539 | 0.82 | HTR1A (0.66) | HRH3SLC6A4HTR1A | |
| SCHEMBL7434240 | 0.82 | SLC6A4 (0.61) | HRH3SLC6A4HTR1AKCNH2 | |
| Oxalic Acid SCHEMBL7437107 | 0.81 | SLC6A4 (0.56) | HRH3SLC6A4HTR1AKCNH2 | |
| Oxalic Acid SCHEMBL4739725 | 0.81 | HTR1A (0.67) | HRH3SLC6A4HTR1A | |
| SCHEMBL7435052 | 0.79 | HRH3 (0.62) | HRH3SLC6A4HTR1A | |
| Oxalic Acid SCHEMBL4784368 | 0.77 | HTR1A (0.61) | HRH3SLC6A4HTR1A | |
| SCHEMBL7435335 | 0.75 | HTR1A (0.68) | HRH3SLC6A4HTR1A | |
| SCHEMBL4921786 | 0.75 | HRH3 (0.76) | HRH3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576766-A1 | Propanolamine derivatives, their preparation and use | NOVO NORDISK A/S (DK) | 1994-01-05 | — | — | EP | claimed |
| EP-0576766-A1 | Propanolamine derivatives, their preparation and use | NOVO NORDISK A/S (DK) | 1994-01-05 | — | — | EP | disclosed |