⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494179 | 0.77 | — | — | |
| SCHEMBL4719477 | 0.71 | KMT2A (0.33) | — | |
| Hydrochloric Acid SCHEMBL11878758 | 0.69 | KMT2A (0.32) | — | |
| SCHEMBL2368471 | 0.66 | CA12 (0.35) | — | |
| SCHEMBL10895319 | 0.64 | — | — | |
| SCHEMBL7435722 | 0.64 | CTSK (0.38) | — | |
| SCHEMBL6446166 | 0.64 | — | — | |
| SCHEMBL9640756 | 0.63 | — | — | |
| SCHEMBL4719612 | 0.62 | LMNA (0.36) | — | |
| SCHEMBL10951106 | 0.60 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681224-A1 | DEGRADATION OF PENICILLIN COMPOUNDS | DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) | 2014-01-08 | — | — | EP | claimed |
| WO-2012117038-A1 | DEGRADATION OF PENICILLIN COMPOUNDS | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-09-07 | — | — | WO | claimed |
| EP-2681224-B1 | DEGRADATION OF PENICILLIN COMPOUNDS | DSM SINOCHEM PHARM NL BV (NL) | 2016-06-22 | — | — | EP | disclosed |
| EP-2681224-A1 | DEGRADATION OF PENICILLIN COMPOUNDS | DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) | 2014-01-08 | — | — | EP | disclosed |
| WO-2012117038-A1 | DEGRADATION OF PENICILLIN COMPOUNDS | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-09-07 | — | — | WO | disclosed |
| EP-0542525-B1 | Antithrombotic agents | LILLY CO ELI (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0837071-A1 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0685489-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |
| EP-0684258-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5430023-A | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-07-04 | — | — | US | disclosed |
| US-5252566-A | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0542525-A2 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| EP-0479489-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1992-04-08 | — | — | EP | disclosed |
| US-4683227-A | CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0211526-A2 | Cephalosporins, their preparation and formulations | ELI LILLY AND COMPANY (US) | 1987-02-25 | — | — | EP | disclosed |
| US-4248868-A | FOR TREATING SYSTEMIC INFECTIONS BY GRAMPOSITIVE AND GRAM NEGATIVE BACTERIA | CIBA-GEIGY CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |
| US-4182866-A | CEPHALOSPORINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-01-08 | — | — | US | disclosed |