Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 4/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 4/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438890 | 0.95 | MMP8 (0.42) | MMP8KLKB1KLK1PKMMME | |
| SCHEMBL7436965 | 0.92 | SMN1; SMN2 (0.40) | MMP8KLKB1KLK1PKMPTPN1 | |
| SCHEMBL9414191 | 0.89 | MME (0.52) | MMP8MMEACEKMT2A | |
| SCHEMBL7441235 | 0.89 | MME (0.46) | MMP8KLKB1KLK1MMEACE | |
| SCHEMBL7428167 | 0.81 | MMP8 (0.43) | MMP8MMEACEPTPN1LMNA | |
| SCHEMBL11008763 | 0.75 | MME (0.68) | MMP8MMEACEABCB11LMNA | |
| SCHEMBL7350611 | 0.74 | KMT2A (0.54) | KMT2AMEN1 | |
| SCHEMBL10947239 | 0.73 | ACE (0.56) | MMEACEABCB11LMNA | |
| SCHEMBL9733367 | 0.73 | MME (0.62) | KLKB1MMEACELMNAKMT2A | |
| SCHEMBL7280398 | 0.73 | MME (0.62) | KLKB1MMEACELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |