Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 5/20 | 0.40 |
| ▸ | CTSB | P07858 | 4/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438890 | 0.96 | MMP8 (0.42) | SMN1; SMN2MMP8KLKB1KLK1PTPN1 | |
| SCHEMBL7434808 | 0.92 | MMP8 (0.43) | MMP8KLKB1KLK1PTPN1KMT2A | |
| SCHEMBL7441235 | 0.91 | MME (0.46) | SMN1; SMN2MMP8KLKB1KLK1KMT2A | |
| SCHEMBL9414191 | 0.82 | MME (0.52) | MMP8KMT2A | |
| SCHEMBL7433554 | 0.78 | CTSL (0.40) | SMN1; SMN2MMP8CTSLCTSBCTSS | |
| SCHEMBL7428167 | 0.76 | MMP8 (0.43) | SMN1; SMN2MMP8PTPN1KMT2AMEN1 | |
| SCHEMBL7434646 | 0.74 | CTSC (0.37) | SMN1; SMN2CTSBCTSSCTSKKMT2A | |
| SCHEMBL7434571 | 0.74 | ADAM17 (0.37) | SMN1; SMN2 | |
| SCHEMBL9864327 | 0.74 | RAB9A (0.52) | SMN1; SMN2CTSLCTSB | |
| SCHEMBL9733346 | 0.74 | RAB9A (0.52) | SMN1; SMN2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |