Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 4/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 4/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439214 | 0.89 | MME (0.52) | MMP8MMEACEKMT2A | |
| SCHEMBL7433554 | 0.87 | CTSL (0.40) | MMP8MMESMN1; SMN2 | |
| SCHEMBL7434808 | 0.81 | MMP8 (0.43) | MMP8MMEACEPTPN1LMNA | |
| SCHEMBL7431662 | 0.81 | KMT2A (0.53) | PTPN1KMT2A | |
| SCHEMBL7435520 | 0.80 | MME (0.41) | MMETSHRKMT2AALOX15 | |
| SCHEMBL7434646 | 0.79 | CTSC (0.37) | TSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7434571 | 0.79 | ADAM17 (0.37) | TSHRSMN1; SMN2 | |
| SCHEMBL7438890 | 0.78 | MMP8 (0.42) | MMP8MMEPTPN1LMNAKMT2A | |
| SCHEMBL7437445 | 0.76 | PTGIR (0.38) | MMP8MMEKMT2ACYP3A4 | |
| SCHEMBL7436965 | 0.76 | SMN1; SMN2 (0.40) | MMP8PTPN1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |