Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 5/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705976 | 0.79 | DPP4 (0.54) | OPRD1DPP4DPP8DPP9AKT1 | |
| SCHEMBL7369287 | 0.79 | DPP4 (0.54) | OPRD1DPP4F2OPRK1NLN | |
| Hydrochloric Acid SCHEMBL7367500 | 0.78 | DPP4 (0.53) | OPRD1DPP4F2OPRK1NLN | |
| SCHEMBL20572087 | 0.75 | OPRD1 (0.48) | OPRD1DPP4DPP8DPP9OPRK1 | |
| SCHEMBL20572088 | 0.75 | OPRD1 (0.48) | OPRD1DPP4DPP8DPP9OPRK1 | |
| SCHEMBL4775313 | 0.74 | OPRD1 (0.59) | OPRD1DPP4DPP8DPP9AKT1 | |
| SCHEMBL7361667 | 0.74 | OPRK1 (0.57) | OPRD1DPP4DPP8DPP9OPRK1 | |
| SCHEMBL7360569 | 0.73 | HDAC8 (0.55) | OPRD1DPP4OPRK1HRH2HRH1 | |
| SCHEMBL7368941 | 0.73 | DPP4 (0.61) | DPP4DPP8DPP9F2OPRK1 | |
| SCHEMBL7367542 | 0.73 | DPP4 (0.51) | OPRD1DPP4DPP8DPP9F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |