Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.42 |
| ▸ | ITGAV | P06756 | 18/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513153 | 0.74 | ITGB3 (0.74) | ITGB3ITGAVITGA2B | |
| SCHEMBL6946801 | 0.63 | ITGB3 (0.75) | ITGB3ITGAVITGA2B | |
| SCHEMBL8516786 | 0.63 | ITGB3 (0.75) | ITGB3ITGAVITGA2B | |
| SCHEMBL8516789 | 0.62 | ITGB3 (0.43) | ITGB3ITGAVITGA2B | |
| SCHEMBL6946793 | 0.62 | ITGB3 (0.60) | ITGB3ITGAVITGA2B | |
| SCHEMBL7442328 | 0.61 | ITGB3 (0.55) | ITGB3ITGAVITGA2BTSHR | |
| SCHEMBL8329426 | 0.59 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7407472 | 0.59 | EGLN1 (0.48) | F10CYP1A2 | |
| SCHEMBL22395393 | 0.59 | CACNA1H (0.43) | F10CYP1A2 | |
| SCHEMBL8325831 | 0.58 | PKM (0.54) | F10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | claimed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | claimed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | claimed |
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |