Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280172 | 0.84 | SMN1; SMN2 (0.49) | NPC1ALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL7437444 | 0.83 | KMT2A (0.64) | NPC1ALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL7435728 | 0.83 | ALDH1A1 (0.46) | NPC1ALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL7426498 | 0.80 | ME2 (0.58) | NPC1ALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL7434260 | 0.80 | USP2 (0.56) | NPC1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7434820 | 0.79 | ALDH1A1 (0.68) | NPC1ALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL7439654 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL7431609 | 0.78 | NPC1 (0.51) | NPC1ALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL7435084 | 0.77 | USP2 (0.76) | ALDH1A1KMT2ALMNAHTTUSP2 | |
| SCHEMBL7431652 | 0.76 | MAPT (0.50) | NPC1ALDH1A1KDM4ETHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |