Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10837614 | 0.86 | SMN1; SMN2 (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7435535 | 0.83 | NPC1 (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7429214 | 0.80 | MEN1 (0.61) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7435890 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7426498 | 0.77 | ME2 (0.58) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7437444 | 0.77 | KMT2A (0.64) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL7438908 | 0.77 | POLB (0.50) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7282013 | 0.76 | PRMT1 (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7434260 | 0.74 | USP2 (0.56) | ALDH1A1MEN1KMT2AKDM4EATM | |
| SCHEMBL7434820 | 0.73 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |