Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.48 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524120 | 0.87 | L3MBTL1 (0.66) | L3MBTL1SERPINH1KMT2AHTTNPC1 | |
| SCHEMBL10426256 | 0.85 | MTNR1A (0.51) | L3MBTL1FFAR1 | |
| SCHEMBL9073611 | 0.84 | ITGB3 (0.51) | FFAR1SMN1; SMN2 | |
| SCHEMBL22362031 | 0.84 | ITGB3 (0.51) | FFAR1SMN1; SMN2 | |
| SCHEMBL27494318 | 0.83 | SERPINH1 (0.46) | L3MBTL1SERPINH1KMT2AHTTACP3 | |
| SCHEMBL10439991 | 0.82 | MAPT (0.47) | L3MBTL1FFAR1SERPINH1KMT2AATM | |
| SCHEMBL6825864 | 0.81 | MMP2 (0.57) | KMT2AHTTCNR2HPGDNPSR1 | |
| SCHEMBL10424824 | 0.80 | TDP1 (0.47) | FFAR1SERPINH1KMT2AATMCNR2 | |
| SCHEMBL10536046 | 0.80 | PDPK1 (0.50) | FFAR1KMT2ACNR2 | |
| SCHEMBL28489153 | 0.78 | FFAR1 (0.61) | L3MBTL1FFAR1KMT2AATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609031-B1 | Process for preparing benzothiazepine derivatives | SHIONOGI & CO (JP) | 1997-08-13 | — | — | EP | disclosed |