Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.64 |
| ▸ | PPARD | Q03181 | 2/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
| ▸ | PPARA | Q07869 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | CASP3 | P42574 | 4/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 2/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432018 | 0.86 | NR1H4 (0.82) | NR1H4PPARDPPARGPPARANPC1 | |
| SCHEMBL7740939 | 0.85 | KMT2A (0.63) | NR1H4PPARDNPC1RAB9AMEN1 | |
| SCHEMBL28869818 | 0.84 | KMT2A (0.75) | NR1H4MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL8085694 | 0.80 | NPC1 (0.80) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL7426358 | 0.80 | KMT2A (0.58) | NR1H4PPARDPPARGPPARANPC1 | |
| SCHEMBL29106507 | 0.78 | MEN1 (0.71) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL2662328 | 0.78 | MEN1 (0.57) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31170867 | 0.78 | MEN1 (0.57) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7449026 | 0.78 | NR1H4 (0.72) | NR1H4PPARDPPARGPPARANPC1 | |
| SCHEMBL20848006 | 0.77 | NPC1 (0.78) | NPC1RAB9AMEN1KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061631-A1 | MODIFIED PENTAPEPTIDE ANTAGONISTS OF THE ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |