Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433413 | 0.87 | NR1H4 (0.74) | KMT2AMEN1NR1H4NPC1RAB9A | |
| SCHEMBL7427460 | 0.86 | NR1H4 (0.76) | KMT2AMEN1NR1H4NPC1RAB9A | |
| SCHEMBL27795055 | 0.82 | PLG (0.60) | KMT2AMEN1NR1H4NPC1RAB9A | |
| SCHEMBL3060113 | 0.81 | ALDH1A1 (0.54) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL7740939 | 0.80 | KMT2A (0.63) | KMT2AMEN1NR1H4NPC1RAB9A | |
| SCHEMBL7435795 | 0.80 | NR1H4 (0.64) | KMT2AMEN1NR1H4NPC1RAB9A | |
| SCHEMBL27852778 | 0.80 | MEN1 (0.57) | KMT2AMEN1NR1H4NPC1RAB9A | |
| SCHEMBL12800038 | 0.79 | P2RX1 (0.58) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL20847994 | 0.77 | NPC1 (0.73) | KMT2AMEN1NPC1RAB9ADEGS1 | |
| SCHEMBL7425090 | 0.77 | SLC16A3 (0.59) | KMT2AMEN1NR1H4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061631-A1 | MODIFIED PENTAPEPTIDE ANTAGONISTS OF THE ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |