Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443714 | 0.89 | RAB9A (0.43) | SMN1; SMN2MAPTPOLBATMMEN1 | |
| SCHEMBL7443775 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTPOLBATMCCR2 | |
| SCHEMBL8297312 | 0.76 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTPOLBATMMEN1 | |
| SCHEMBL7445788 | 0.75 | CA1 (0.45) | — | |
| SCHEMBL7438236 | 0.75 | CA1 (0.45) | — | |
| SCHEMBL7443440 | 0.74 | CA1 (0.48) | — | |
| SCHEMBL8334464 | 0.73 | CTSS (0.56) | SMN1; SMN2MAPTPOLBATMMEN1 | |
| SCHEMBL7440652 | 0.73 | CTSK (0.47) | MAPTATM | |
| SCHEMBL7442497 | 0.73 | CTSK (0.49) | POLBMEN1KMT2A | |
| SCHEMBL7429906 | 0.73 | CTSK (0.49) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |