Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 4/20 | 0.32 |
| ▸ | PYGM | P11217 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292459 | 0.86 | TSHR (0.43) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL6292506 | 0.82 | MAPT (0.39) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL7017903 | 0.78 | ALDH1A1 (0.41) | LMNAMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL7436392 | 0.76 | PYGL (0.39) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL7441431 | 0.74 | PYGL (0.39) | LMNAMAPTNPSR1KMT2AKDM4E | |
| SCHEMBL7025273 | 0.74 | TBXA2R (0.41) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL7017155 | 0.74 | KDM4E (0.39) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL6293743 | 0.74 | USP7 (0.36) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL6293440 | 0.72 | ADORA3 (0.47) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL6293653 | 0.70 | KDM4E (0.51) | LMNAMAPTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062795-A9 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2002-10-10 | — | — | WO | disclosed |