Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 15/20 | 0.39 |
| ▸ | PYGM | P11217 | 15/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017155 | 0.89 | KDM4E (0.39) | PYGLPYGMKDM4EALDH1A1GLA | |
| SCHEMBL7027088 | 0.87 | GSK3B (0.33) | — | |
| SCHEMBL6296672 | 0.86 | TSHR (0.47) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL7017903 | 0.84 | ALDH1A1 (0.41) | PYGLPYGMKDM4EALDH1A1GLA | |
| SCHEMBL7025273 | 0.80 | TBXA2R (0.41) | PYGLPYGMKDM4EALDH1A1GLA | |
| SCHEMBL7441431 | 0.80 | PYGL (0.39) | PYGLPYGMKDM4EALDH1A1GLA | |
| SCHEMBL6297217 | 0.79 | CDK1 (0.41) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7436263 | 0.76 | LMNA (0.35) | PYGLPYGMKDM4EALDH1A1GLA | |
| SCHEMBL6293330 | 0.76 | TSHR (0.45) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL6293653 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062795-A9 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2002-10-10 | — | — | WO | disclosed |