Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 0.63 |
| ▸ | HTR3A | P46098 | 4/20 | 0.63 |
| ▸ | DRD2 | P14416 | 3/20 | 0.63 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.63 |
| ▸ | HTR3B | O95264 | 2/20 | 0.63 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.63 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | HTR5A | P47898 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8870896 | 0.99 | HTR4 (0.62) | HTR4HTR3ADRD2HTR3EHTR3B | |
| SCHEMBL7433789 | 0.86 | DRD2 (0.52) | HTR4HTR3ADRD2HTR3EHTR3B | |
| SCHEMBL7918548 | 0.82 | HTR3A (0.69) | HTR4HTR3ADRD2HTR3EHTR3B | |
| SCHEMBL8854577 | 0.80 | DRD2 (0.74) | HTR4HTR3ADRD2HTR3EHTR3B | |
| SCHEMBL11173712 | 0.78 | HTR4 (0.65) | HTR4HTR3ADRD2HTR3EHTR3B | |
| SCHEMBL7354795 | 0.78 | HTR4 (0.59) | HTR4HTR3ADRD2HTR3EHTR3B | |
| SCHEMBL7385997 | 0.78 | DRD2 (0.75) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL10721765 | 0.78 | HTR4 (0.64) | HTR4HTR3ADRD2HTR3EHTR3B | |
| SCHEMBL9021828 | 0.78 | DRD2 (0.78) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL11179659 | 0.78 | HTR4 (0.61) | HTR4HTR3ADRD2HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748807-A1 | Derivatives of N-(1,4-diazabicyclo(2.2.2)-oct-2-yl)methyl benzamide, their preparation and their therapeutical use | SYNTHELABO (FR) | 1996-12-18 | — | — | EP | disclosed |