Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020208 | 0.90 | KDM4E (0.39) | — | |
| SCHEMBL6293480 | 0.90 | CACNA1C (0.42) | CACNA1C | |
| SCHEMBL7429502 | 0.87 | CYP2C9 (0.42) | CACNA1C | |
| SCHEMBL6293657 | 0.83 | CTSS (0.40) | CTSSCTSK | |
| SCHEMBL7441431 | 0.83 | PYGL (0.39) | CACNA1C | |
| SCHEMBL7433250 | 0.82 | CACNA1C (0.41) | CACNA1C | |
| SCHEMBL7433258 | 0.82 | CACNA1C (0.41) | CACNA1C | |
| SCHEMBL6297263 | 0.80 | CACNA1C (0.49) | CACNA1C | |
| SCHEMBL7437504 | 0.79 | NR3C2 (0.37) | — | |
| SCHEMBL7435806 | 0.79 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062795-A9 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2002-10-10 | — | — | WO | claimed |