Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441431 | 0.91 | PYGL (0.39) | KDM4EKMT2ATSHRLMNAHSD17B10 | |
| SCHEMBL6293510 | 0.89 | CYP2C9 (0.54) | CYP2C9KDM4EMEN1KMT2ATSHR | |
| SCHEMBL7436372 | 0.87 | P2RX7 (0.34) | CACNA1C | |
| SCHEMBL7433250 | 0.86 | CACNA1C (0.41) | CYP2C9KDM4EKMT2ATSHRLMNA | |
| SCHEMBL7433258 | 0.86 | CACNA1C (0.41) | CYP2C9KDM4EKMT2ATSHRLMNA | |
| SCHEMBL7027096 | 0.85 | TSHR (0.35) | TSHR | |
| SCHEMBL7431137 | 0.85 | ALOX15 (0.36) | CYP2C9KDM4EMEN1KMT2ATSHR | |
| SCHEMBL7437504 | 0.83 | NR3C2 (0.37) | CYP2C9TSHRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7435806 | 0.83 | MEN1 (0.39) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL7017886 | 0.83 | CACNA1D (0.31) | CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062795-A9 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2002-10-10 | — | — | WO | disclosed |