Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292367 | 0.89 | NR3C2 (0.49) | MEN1KMT2ARCE1MAPTNPSR1 | |
| SCHEMBL7441431 | 0.85 | PYGL (0.39) | KMT2AMAPTNPSR1KDM4EALDH1A1 | |
| SCHEMBL7023193 | 0.84 | MTNR1A (0.37) | KMT2ACNR1CNR2 | |
| SCHEMBL7433747 | 0.84 | ALDH1A1 (0.37) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL7434003 | 0.83 | CACNA1D (0.33) | MEN1KMT2ANR3C2ALDH1A1HPGD | |
| SCHEMBL7429502 | 0.83 | CYP2C9 (0.42) | MEN1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL7017886 | 0.83 | CACNA1D (0.31) | CACNA1D | |
| SCHEMBL7020208 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL7018953 | 0.81 | GAA (0.41) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6292356 | 0.81 | KMT2A (0.33) | MEN1KMT2ARCE1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062795-A9 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2002-10-10 | — | — | WO | claimed |