Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 9/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HK1 | P19367 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CD74 | P04233 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24549320 | 0.84 | TDP1 (0.61) | TBXA2RHTTLMNATDP1ALDH1A1 | |
| SCHEMBL31633144 | 0.82 | TSHR (0.66) | TBXA2RHTTMAPTLMNAALDH1A1 | |
| SCHEMBL3718063 | 0.81 | RAB9A (0.67) | TBXA2RHTTMAPTLMNAHTR3A | |
| SCHEMBL1169953 | 0.80 | LMNA (0.70) | TBXA2RHTTMAPTHKDC1LMNA | |
| SCHEMBL8185055 | 0.80 | DCTPP1 (0.50) | HTTMAPTLMNAAGTR1AGTR2 | |
| SCHEMBL29467867 | 0.78 | KCNH2 (0.59) | HTTMAPTHKDC1LMNATDP1 | |
| SCHEMBL28708639 | 0.78 | KCNH2 (0.59) | HTTMAPTHKDC1LMNATDP1 | |
| SCHEMBL27398016 | 0.77 | SOS1 (0.59) | HTTMAPTLMNAALDH1A1 | |
| SCHEMBL25229550 | 0.76 | KCNH2 (0.53) | TBXA2RAGTR1AGTR2 | |
| SCHEMBL30336663 | 0.76 | KCNH2 (0.53) | TBXA2RAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628549-B1 | New 1-phenylmethyl benzimidazole piperazine derivatives | ESPANOLA DE PRODUCTOS FAB (ES) | 2000-12-06 | — | — | EP | disclosed |
| US-5672604-A | SEROTONIN RECEPTOR ANTAGONISTS | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS (FAES) (ES) | 1997-09-30 | — | — | US | disclosed |