Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 2/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12771510 | 0.84 | TNF (0.69) | TDP1ALDH1A1KDM4EKMT2AHTT | |
| SCHEMBL7436459 | 0.84 | TBXA2R (0.52) | TDP1ALDH1A1HTTPOLBLMNA | |
| SCHEMBL1169953 | 0.83 | LMNA (0.70) | ALDH1A1KDM4EKMT2AHTTCFTR | |
| SCHEMBL8185055 | 0.82 | DCTPP1 (0.50) | TDP1ALDH1A1KDM4EKMT2AHTT | |
| SCHEMBL4083319 | 0.81 | TP53 (0.63) | ALDH1A1KMT2ALMNATP53TNF | |
| SCHEMBL22465204 | 0.81 | TBXA2R (0.52) | TDP1ALDH1A1KDM4EKMT2AHTT | |
| SCHEMBL4097969 | 0.80 | NOD1 (0.71) | TDP1ALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL27398016 | 0.79 | SOS1 (0.59) | ALDH1A1KMT2AHTTLMNATP53 | |
| SCHEMBL22955866 | 0.77 | KMT2A (0.66) | TDP1ALDH1A1KDM4EKMT2AHTT | |
| SCHEMBL29808487 | 0.77 | KMT2A (0.66) | TDP1ALDH1A1KDM4EKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133098-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-06-23 | — | — | WO | disclosed |