Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP7 | P09237 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MMP12 | P39900 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | CIT | O14578 | 1/20 | 0.41 |
| ▸ | TPH1 | P17752 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431334 | 0.78 | KMT2A (0.50) | LDHA | |
| SCHEMBL7430899 | 0.78 | ALDH1A1 (0.44) | MMP1MMP7MMP8MMP12MMP13 | |
| SCHEMBL6242807 | 0.73 | LDHA (0.56) | MMP1LDHACITGPR142SLC6A4 | |
| SCHEMBL3634298 | 0.73 | LDHA (0.56) | MMP1LDHACITGPR142SLC6A4 | |
| SCHEMBL6242805 | 0.73 | LDHA (0.56) | MMP1LDHACITGPR142SLC6A4 | |
| Hydrochloric Acid SCHEMBL10890977 | 0.72 | LDHA (0.54) | MMP1LDHACITTPH1GPR142 | |
| SCHEMBL24942192 | 0.71 | LDHA (0.53) | LDHATPH1GPR142SLC6A4CYP1A2 | |
| SCHEMBL1311287 | 0.70 | LDHA (0.59) | LDHATPH1DPP4FAPDPP8 | |
| SCHEMBL7250996 | 0.70 | LDHA (0.59) | LDHATPH1DPP4FAPDPP8 | |
| SCHEMBL1309076 | 0.70 | LDHA (0.59) | LDHATPH1DPP4FAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |