Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7444380 | 0.99 | LMNA (0.39) | LMNAMAPTSMN1; SMN2NPSR1LTA4H | |
| Acetic Acid SCHEMBL7435017 | 0.97 | MAPT (0.38) | LMNAMAPTSMN1; SMN2NPSR1LTA4H | |
| SCHEMBL7435447 | 0.93 | LMNA (0.38) | LMNAMAPTSMN1; SMN2NPSR1LTA4H | |
| SCHEMBL7437169 | 0.93 | LMNA (0.31) | LMNAMAPTSMN1; SMN2NPSR1LTA4H | |
| SCHEMBL7434579 | 0.92 | CA2 (0.35) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7439952 | 0.91 | CA2 (0.38) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7440399 | 0.91 | CA2 (0.38) | LMNAMAPTSMN1; SMN2NPSR1LTA4H | |
| SCHEMBL7429561 | 0.90 | CA2 (0.37) | NPSR1ALDH1A1KMT2ADRD2 | |
| SCHEMBL7435691 | 0.89 | GAA (0.41) | LMNAMAPTSMN1; SMN2NPSR1LTA4H | |
| SCHEMBL7446102 | 0.89 | LMNA (0.39) | LMNAMAPTALDH1A1MTNR1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | claimed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |