Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434853 | 0.98 | MTNR1A (0.40) | LMNAMCHR1MTNR1AMAPTNPC1 | |
| SCHEMBL7431667 | 0.94 | LMNA (0.37) | LMNAMCHR1MTNR1AMAPTNPC1 | |
| SCHEMBL7437776 | 0.91 | LMNA (0.38) | LMNAMCHR1MTNR1AMAPTNPC1 | |
| SCHEMBL7434579 | 0.90 | CA2 (0.35) | LMNAMAPTNPC1GAAALDH1A1 | |
| SCHEMBL7436658 | 0.89 | LMNA (0.39) | LMNAMTNR1AMAPTGAAALDH1A1 | |
| SCHEMBL7437169 | 0.89 | LMNA (0.31) | LMNAMAPTFFAR1 | |
| SCHEMBL7440399 | 0.89 | CA2 (0.38) | LMNAMCHR1MAPTNPC1ADRA1D | |
| SCHEMBL7428117 | 0.89 | LMNA (0.43) | LMNAMCHR1MTNR1AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL7444380 | 0.88 | LMNA (0.39) | LMNAMTNR1AMAPTALDH1A1 | |
| SCHEMBL7439952 | 0.88 | CA2 (0.38) | LMNAMCHR1MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |