SCHEMBL7437169

SCHEMBL7437169

Cc1cc2c(cc1C)OC(C(O)CNC1CCN(C(C(N)=O)c3c(C)cccc3C)CC1)CO2

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
F10 P00742 1/20 0.31
FFAR1 O14842 2/20 0.30
LTA4H P09960 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7439952 0.93 CA2 (0.38) LMNAMAPTSMN1; SMN2NPSR1FFAR1
SCHEMBL7436658 0.93 LMNA (0.39) LMNAMAPTSMN1; SMN2NPSR1LTA4H
SCHEMBL7434579 0.92 CA2 (0.35) LMNAMAPTSMN1; SMN2NPSR1
Hydrochloric Acid SCHEMBL7444380 0.92 LMNA (0.39) LMNAMAPTSMN1; SMN2NPSR1LTA4H
SCHEMBL7429561 0.92 CA2 (0.37) NPSR1FFAR1MEN1KMT2A
SCHEMBL7440399 0.91 CA2 (0.38) LMNAMAPTSMN1; SMN2NPSR1F10
Acetic Acid SCHEMBL7435017 0.91 MAPT (0.38) LMNAMAPTSMN1; SMN2NPSR1LTA4H
SCHEMBL7434853 0.90 MTNR1A (0.40) LMNAMAPTFFAR1
SCHEMBL7446102 0.89 LMNA (0.39) LMNAMAPTFFAR1
SCHEMBL7435447 0.88 LMNA (0.38) LMNAMAPTSMN1; SMN2NPSR1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4499100-A CARDIOUVASCULAR DISORDERS SYNTEX (U.S.A.) INC. (US) 1985-02-12 US disclosed