Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 10/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6789523 | 0.84 | KMT2A (0.48) | PKMKDM4EALDH1A1ADAM17 | |
| SCHEMBL6298944 | 0.81 | TDO2 (0.52) | AKR1C3AKR1C1F10PKM | |
| SCHEMBL2266915 | 0.77 | PKM (0.73) | F10PKMALDH1A1 | |
| SCHEMBL6267145 | 0.76 | SMN1; SMN2 (0.60) | AKR1C3AKR1C1ALDH1A1ADAM17 | |
| Hydrochloric Acid SCHEMBL5733824 | 0.76 | PKM (0.71) | F10PKMALDH1A1 | |
| SCHEMBL4041537 | 0.75 | LMNA (0.53) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6301203 | 0.73 | F10 (0.48) | F10ADAM17 | |
| SCHEMBL8073053 | 0.73 | F10 (0.41) | AKR1C3AKR1C1F10PKMCTDSP1 | |
| SCHEMBL6793272 | 0.73 | KMT2A (0.59) | AKR1C3AKR1C1PKMKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6730981 | 0.73 | F10 (0.49) | AKR1C3AKR1C1F10PKMEIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880516-A1 | AMINOHETEROCYCLIC COMPOUNDS WITH ANTITHROMBOTIC/ANTICOAGULANT EFFECT | ZENECA LIMITED (GB) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997029104-A1 | AMINOHETEROCYCLIC COMPOUNDS WITH ANTITHROMBOTIC/ANTICOAGULANT EFFECT | ZENECA LIMITED (GB) | 1997-08-14 | — | — | WO | disclosed |