Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436813 | 0.73 | AKR1C3 (0.50) | F10ALDH1A1ADAM17PKMAKR1C3 | |
| SCHEMBL6301308 | 0.70 | PKM (0.45) | F10MMP1MMP13ADAM17POLB | |
| SCHEMBL6789523 | 0.69 | KMT2A (0.48) | ALDH1A1ADAM17PKM | |
| SCHEMBL6298944 | 0.68 | TDO2 (0.52) | F10PKMAKR1C3AKR1C1 | |
| SCHEMBL2266915 | 0.65 | PKM (0.73) | F10ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL5733824 | 0.64 | PKM (0.71) | F10ALDH1A1PKM | |
| SCHEMBL4625949 | 0.62 | SNCA (0.51) | F10ALDH1A1MMP1MMP13 | |
| SCHEMBL948719 | 0.61 | ALDH1A1 (0.56) | ALDH1A1POLBCTDSP1TDP1L3MBTL1 | |
| SCHEMBL5804011 | 0.60 | ALDH1A1 (0.56) | ALDH1A1POLBPKMAKR1C3AKR1C1 | |
| SCHEMBL5804014 | 0.60 | ALDH1A1 (0.56) | ALDH1A1POLBPKMAKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022869-A | Aminoheterocyclic compounds with antithrombotic/anticoagulant effect | ZENECA LIMITED (GB) | 2000-02-08 | — | — | US | disclosed |