Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349841 | 0.89 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL5410684 | 0.79 | SIGMAR1 (0.43) | SIGMAR1CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL27460410 | 0.79 | LMNA (0.41) | ALDH1A1 | |
| SCHEMBL8398246 | 0.79 | SIGMAR1 (0.43) | SIGMAR1CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL585515 | 0.79 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7746454 | 0.78 | MAOA (0.44) | SIGMAR1L3MBTL1 | |
| SCHEMBL8350621 | 0.76 | SIGMAR1 (0.44) | SIGMAR1 | |
| SCHEMBL19090603 | 0.76 | SIGMAR1 (0.50) | SIGMAR1L3MBTL1 | |
| SCHEMBL108633 | 0.76 | LMNA (0.54) | SIGMAR1L3MBTL1 | |
| SCHEMBL11644542 | 0.74 | SIGMAR1 (0.48) | SIGMAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062795-A9 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2002-10-10 | — | — | WO | disclosed |