Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429940 | 0.91 | PAX8 (0.49) | PAX8HTR1ADRD2HTR2AHRH3 | |
| Hydrochloric Acid SCHEMBL10459287 | 0.90 | PAX8 (0.48) | PAX8HTR1ADRD2HTR2AHRH3 | |
| SCHEMBL7440209 | 0.87 | MEN1 (0.50) | PAX8MEN1KMT2AHTR1ADRD2 | |
| SCHEMBL7438853 | 0.85 | MEN1 (0.49) | PAX8MEN1KMT2AHTR1ADRD2 | |
| SCHEMBL7439679 | 0.84 | KDM4E (0.46) | MEN1KMT2AHTR1ADRD2HTR2A | |
| SCHEMBL10460775 | 0.83 | ABCB11 (0.57) | PAX8MEN1KMT2AHTR1ADRD2 | |
| SCHEMBL7446953 | 0.83 | HRH1 (0.54) | PAX8MEN1HTR1ADRD2HTR2A | |
| SCHEMBL7442321 | 0.82 | PAX8 (0.51) | PAX8MEN1KMT2AHTR1ADRD2 | |
| SCHEMBL7446850 | 0.82 | PAX8 (0.51) | PAX8MEN1HTR1ADRD2HTR2A | |
| SCHEMBL7438495 | 0.82 | KDM4E (0.43) | HTR1ADRD2HTR2AHRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070087-A | Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |