Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435551 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1MEN1KMT2AACHE | |
| SCHEMBL7436873 | 0.84 | PAX8 (0.47) | KDM4EALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL7438495 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1ACHEBCHEMAPK1 | |
| SCHEMBL10718735 | 0.77 | ABCB11 (0.50) | KDM4EALDH1A1MEN1KMT2AACHE | |
| SCHEMBL7429940 | 0.77 | PAX8 (0.49) | KDM4EALDH1A1ACHEMAPK1HTR1A | |
| Hydrochloric Acid SCHEMBL10459287 | 0.76 | PAX8 (0.48) | KDM4EALDH1A1ACHEMAPK1HTR1A | |
| Oxalic Acid SCHEMBL10749298 | 0.76 | ABCB11 (0.49) | KDM4EALDH1A1MEN1KMT2AACHE | |
| SCHEMBL7437843 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1MEN1KMT2AACHE | |
| SCHEMBL7441615 | 0.74 | KDM4E (0.45) | KDM4EALDH1A1KMT2ASLC6A1ACHE | |
| SCHEMBL7435875 | 0.72 | ABCB11 (0.45) | KDM4EALDH1A1MEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070087-A | Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |