Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.85 |
| ▸ | MMP9 | P14780 | 10/20 | 0.85 |
| ▸ | MMP1 | P03956 | 3/20 | 0.77 |
| ▸ | MMP3 | P08254 | 2/20 | 0.77 |
| ▸ | MMP7 | P09237 | 2/20 | 0.77 |
| ▸ | MMP13 | P45452 | 2/20 | 0.77 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MMP14 | P50281 | 4/20 | 0.56 |
| ▸ | ADAM10 | O14672 | 3/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | MMP12 | P39900 | 2/20 | 0.52 |
| ▸ | CPB1 | P15086 | 1/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365919 | 1.00 | MMP2 (0.85) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL6122901 | 0.93 | MMP2 (0.90) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL3619933 | 0.87 | MMP2 (0.80) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL15238617 | 0.86 | MMP2 (0.76) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL10619187 | 0.86 | MMP2 (0.62) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL7894794 | 0.85 | MMP2 (0.73) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL5655210 | 0.84 | MMP2 (0.75) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL14328287 | 0.83 | MMP9 (0.59) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL13426068 | 0.83 | RAB9A (0.62) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL29397920 | 0.82 | ALDH1A1 (0.63) | MMP2MMP9MMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328932-A | Cardiovascular disorders, antiischemic agents and stroke | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5248673-A | Antiischemic, anticoagulant | BRISTOL-MYERS SQUIBB CO. (US) | 1993-09-28 | — | — | US | disclosed |