Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | TSHR | P16473 | 5/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.63 |
| ▸ | PPARG | P37231 | 7/20 | 0.63 |
| ▸ | PPARD | Q03181 | 7/20 | 0.63 |
| ▸ | PPARA | Q07869 | 7/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TLR2 | O60603 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | FABP4 | P15090 | 2/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.63 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL28824681 | 1.00 | LMNA (0.79) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL7894497 | 1.00 | LMNA (0.79) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL1539243 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL15111284 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Pimelic Acid SCHEMBL28197361 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL3065275 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Acetic Acid SCHEMBL7845679 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Octanedioate SCHEMBL15111383 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Octanedioate SCHEMBL1539264 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Acetic Acid SCHEMBL28242014 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119655262-A | Seed coating composition | 玉米产品开发公司 | 2025-03-21 | — | — | CN | claimed |
| US-20240020529-A1 | PCT/US21/056841 | ISP INVESTMENTS LLC (US) | 2024-01-18 | — | — | US | claimed |
| EP-4236953-A1 | METHOD AND SYSTEM FOR PREDICTING PROPERTIES OF AMORPHOUS SOLID DISPERSIONS USING MACHINE LEARNING | ISP Investments LLC (US) | 2023-09-06 | — | — | EP | claimed |
| CN-111212855-B | Microfibrillated cellulose as a cross-linking agent | 宝丽格公司 | 2023-03-24 | — | — | CN | claimed |
| CN-115038680-A | Glidant composition | 玉米产品开发公司 | 2022-09-09 | — | — | CN | claimed |
| CN-114501990-A | Seed coating composition | 玉米产品开发公司 | 2022-05-13 | — | — | CN | claimed |
| WO-2022093951-A1 | METHOD AND SYSTEM FOR PREDICTING PROPERTIES OF AMORPHOUS SOLID DISPERSIONS USING MACHINE LEARNING | ISP INVESTMENTS LLC (US) | 2022-05-05 | — | — | WO | claimed |
| WO-2022036033-A2 | SOLID STATE FORMS OF AN ORGANIC COMPOUND | SERVIER PHARMACEUTICALS, LLC (US) | 2022-02-17 | — | — | WO | claimed |
| US-20200397756-A1 | A STABLE PHARMACEUTICAL COMPOSITION OF POORLY SOLUBLE NONSTEROIDAL ANTIANDROGENS | KASHIV BIOSCIENCES, LLC | 2020-12-24 | — | — | US | claimed |
| CN-111212855-A | Microfibrillated cellulose as a cross-linking agent | 宝丽格公司 | 2020-05-29 | — | — | CN | claimed |
| WO-2019155416-A2 | A STABLE PHARMACEUTICAL COMPOSITION OF POORLY SOLUBLE NONSTEROIDAL ANTIANDROGENS | KASHIV PHARMA LLC (US) | 2019-08-15 | — | — | WO | claimed |
| US-20130237609-A1 | CELLULOSE DERIVATIVES FOR ENHANCING BIOAVAILABILITY OF FLAVONOIDS | EDGAR KEVIN J (US) | 2013-09-12 | — | — | US | claimed |
| WO-2013063336-A1 | REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS AND EFFICIENT METHODS OF PREPARING THEM | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2013-05-02 | — | — | WO | claimed |
| WO-2013058751-A1 | CELLULOSE DERIVATIVES FOR ENHANCING BIOAVAILABILITY OF FLAVONOIDS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2013-04-25 | — | — | WO | claimed |
| EP-0486863-B1 | Antiacid compositions with prolonged gastric residence time | BAYER AG (DE) | 1995-08-30 | — | — | EP | claimed |
| US-5213794-A | Calcium polycarbophil, anionic polymer binder | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | claimed |
| CN-119655262-A | Seed coating composition | 玉米产品开发公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-115038680-B | Glidant composition | 玉米产品开发公司 | 2024-12-13 | — | — | CN | disclosed |
| US-5213794-A | Calcium polycarbophil, anionic polymer binder | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| US-3997453-A | QUATERNARY AMMONIUM, ANIONIC ORGANIC SULFONATE | COLGATE-PALMOLIVE COMPANY (US) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237609-A1 | CELLULOSE DERIVATIVES FOR ENHANCING BIOAVAILABILITY OF FLAVONOIDS | KEAP1, NQO1, ABCG2 | LMNA 1145/4885TSHR 4821/4885NFKB1 81/4885 |
| US-20200397756-A1 | A STABLE PHARMACEUTICAL COMPOSITION OF POORLY SOLUBLE NONSTEROIDAL ANTIANDROGENS | AR, SHBG, SULT2A1 | LMNA 3663/4885TSHR 4530/4885NFKB1 1564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.