Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432092 | 0.90 | ACE (0.41) | ACEPOLBNPSR1TSHRALDH1A1 | |
| SCHEMBL7431972 | 0.89 | ACE (0.37) | ACEPOLBNPSR1TSHRALDH1A1 | |
| SCHEMBL7446529 | 0.88 | ACE (0.41) | ACEPOLBNPSR1TSHRALDH1A1 | |
| SCHEMBL7439156 | 0.84 | MME (0.44) | ACEPOLBNPSR1TSHRALDH1A1 | |
| SCHEMBL7442316 | 0.82 | ALDH1A1 (0.51) | ACEPOLBNPSR1TSHRALDH1A1 | |
| SCHEMBL7426794 | 0.79 | POLB (0.37) | POLBALDH1A1MEN1HTTKMT2A | |
| SCHEMBL7437103 | 0.79 | MME (0.43) | ALDH1A1PKM | |
| SCHEMBL7435392 | 0.79 | MME (0.43) | ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL7426848 | 0.77 | CPB2 (0.38) | ACEALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL7440468 | 0.76 | POLB (0.37) | POLBNPSR1TSHRALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |