Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435392 | 1.00 | MME (0.43) | MMECPA3FOLH1ALDH1A1PKM | |
| SCHEMBL7432083 | 0.90 | ACE (0.44) | MMECPA3FOLH1ALDH1A1PKM | |
| SCHEMBL7431966 | 0.89 | MEN1 (0.41) | MMECPA3FOLH1ALDH1A1PKM | |
| SCHEMBL7446522 | 0.88 | CPA3 (0.44) | MMECPA3FOLH1ALDH1A1PKM | |
| SCHEMBL7442303 | 0.84 | ALDH1A1 (0.53) | CPA3FOLH1ALDH1A1PKM | |
| SCHEMBL7439151 | 0.84 | MME (0.46) | MMECPA3FOLH1ALDH1A1PKM | |
| SCHEMBL7435805 | 0.82 | CPA3 (0.38) | MMECPA3FOLH1ALDH1A1PKM | |
| SCHEMBL7426791 | 0.79 | CPA3 (0.38) | MMECPA3FOLH1ALDH1A1PKM | |
| SCHEMBL7437110 | 0.79 | ACE (0.40) | ALDH1A1PKM | |
| SCHEMBL7440464 | 0.76 | FOLH1 (0.41) | MMECPA3FOLH1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |