Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445702 | 0.79 | ACHE (0.40) | POLBNPSR1HSD17B2TSHRALDH1A1 | |
| SCHEMBL7440464 | 0.78 | FOLH1 (0.41) | ALDH1A1PKMHPGDMEN1KMT2A | |
| SCHEMBL7446529 | 0.78 | ACE (0.41) | POLBNPSR1TSHRALDH1A1PKM | |
| SCHEMBL7428792 | 0.78 | CYP2D6 (0.45) | POLBNPSR1KMT2A | |
| SCHEMBL7428456 | 0.78 | PLA2G10 (0.45) | POLBNPSR1HSD17B2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7439156 | 0.77 | MME (0.44) | POLBNPSR1TSHRALDH1A1PKM | |
| SCHEMBL7437110 | 0.76 | ACE (0.40) | POLBNPSR1TSHRALDH1A1PKM | |
| SCHEMBL7426522 | 0.76 | MAPT (0.43) | POLBNPSR1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7432645 | 0.76 | ENPP2 (0.47) | POLBNPSR1TSHRALDH1A1HPGD | |
| SCHEMBL7442316 | 0.75 | ALDH1A1 (0.51) | POLBNPSR1TSHRALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |