Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442963 | 0.79 | HTR1A (0.51) | HTR1ASLC6A4HRH3LTA4HKDM4E | |
| SCHEMBL7427779 | 0.78 | SLC7A5 (0.61) | HTR1ASLC6A4HRH3LTA4HSLC6A2 | |
| SCHEMBL7444415 | 0.77 | HRH3 (0.49) | HTR1ASLC6A4HRH3LTA4HKDM4E | |
| SCHEMBL7434240 | 0.77 | SLC6A4 (0.61) | HTR1ASLC6A4HRH3LTA4HSLC6A2 | |
| SCHEMBL17267470 | 0.76 | SLC7A5 (0.65) | HTR1ASLC6A4HRH3KDM4ESLC6A2 | |
| SCHEMBL7435335 | 0.75 | HTR1A (0.68) | HTR1ASLC6A4HRH3LTA4HSLC6A2 | |
| SCHEMBL17278128 | 0.74 | SLC7A5 (0.66) | HTR1ASLC6A4HRH3KDM4ESLC6A2 | |
| SCHEMBL17267500 | 0.74 | SLC7A5 (0.66) | HTR1ASLC6A4HRH3KDM4ESLC6A2 | |
| SCHEMBL7435052 | 0.74 | HRH3 (0.62) | HTR1ASLC6A4HRH3LTA4H | |
| Oxalic Acid SCHEMBL4739539 | 0.73 | HTR1A (0.66) | HTR1ASLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576766-A1 | Propanolamine derivatives, their preparation and use | NOVO NORDISK A/S (DK) | 1994-01-05 | — | — | EP | claimed |
| EP-0576766-A1 | Propanolamine derivatives, their preparation and use | NOVO NORDISK A/S (DK) | 1994-01-05 | — | — | EP | disclosed |