Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ACE | P12821 | 10/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438308 | 0.89 | KMT2A (0.39) | KMT2AACEMEN1ALDH1A1FKBP1A | |
| SCHEMBL7437645 | 0.80 | ACE (0.41) | KMT2AACEMEN1ALDH1A1TP53 | |
| SCHEMBL7432368 | 0.79 | LMNA (0.43) | KMT2AACEMEN1ALDH1A1CYP3A4 | |
| SCHEMBL7440462 | 0.74 | ACE (0.45) | ACE | |
| SCHEMBL7439237 | 0.73 | ACE (0.41) | ACE | |
| SCHEMBL7425893 | 0.72 | KMT2A (0.44) | KMT2AMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL7432535 | 0.71 | HSD11B1 (0.45) | KMT2AMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL7438304 | 0.70 | ACE (0.40) | KMT2AACEMEN1ALDH1A1CYP3A4 | |
| SCHEMBL7434183 | 0.70 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7445427 | 0.69 | ALDH1A1 (0.41) | KMT2AACEMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |