Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429820 | 0.79 | ATM (0.48) | LMNACYP3A4CYP2C19ALDH1A1ATM | |
| SCHEMBL7432917 | 0.78 | ATM (0.47) | LMNACYP3A4CYP2C19ALDH1A1ATM | |
| SCHEMBL7435488 | 0.75 | CYP3A4 (0.36) | LMNACYP3A4CYP2C19ALDH1A1ATM | |
| SCHEMBL11176413 | 0.73 | ALDH1A1 (0.35) | LMNACA1CA2CA4CA7 | |
| SCHEMBL14419736 | 0.71 | LMNA (0.57) | LMNACA12CA1CA2CA3 | |
| SCHEMBL14419799 | 0.71 | LMNA (0.57) | LMNACA12CA1CA2CA3 | |
| SCHEMBL2330982 | 0.70 | ADRB1 (0.44) | CYP3A4MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL11839058 | 0.70 | ADRB1 (0.44) | CYP3A4MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL6431728 | 0.69 | CYP3A4 (0.34) | CYP3A4CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL11183482 | 0.69 | ALDH1A1 (0.33) | LMNACYP3A4CYP2C19ALDH1A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |