Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429820 | 0.86 | ATM (0.48) | CYP3A4CYP2C19ATMLMNAMEN1 | |
| SCHEMBL7438106 | 0.85 | GAA (0.34) | ATMMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7432917 | 0.84 | ATM (0.47) | CYP3A4CYP2C19ATMLMNAMEN1 | |
| SCHEMBL7434230 | 0.82 | P2RX7 (0.38) | CYP2C19ATMNOTUMP2RX7MEN1 | |
| SCHEMBL11839058 | 0.82 | ADRB1 (0.44) | CYP3A4MEN1CYP2D6CYP2C9KMT2A | |
| SCHEMBL2330982 | 0.82 | ADRB1 (0.44) | CYP3A4MEN1CYP2D6CYP2C9KMT2A | |
| SCHEMBL7437442 | 0.78 | TSHR (0.45) | LMNANPSR1HTTCHRM2CHRM1 | |
| SCHEMBL7446255 | 0.78 | KDM4E (0.41) | LMNAKMT2ANPSR1ALDH1A1POLB | |
| SCHEMBL7434817 | 0.76 | LMNA (0.51) | CYP3A4CYP2C19LMNAMEN1CYP2D6 | |
| SCHEMBL7437674 | 0.75 | LMNA (0.46) | CYP3A4CYP2C19ATMNOTUMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |