Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437727 | 0.82 | OPRK1 (0.44) | OPRK1OPRM1OPRD1BCHEMEN1 | |
| SCHEMBL6398255 | 0.77 | AOC3 (0.50) | TAAR1MEN1KMT2AAOC3 | |
| SCHEMBL11206337 | 0.76 | KDM4E (0.45) | OPRK1OPRM1OPRD1TAAR1MEN1 | |
| SCHEMBL11573309 | 0.75 | OPRK1 (0.64) | OPRK1OPRM1OPRD1BCHETAAR1 | |
| SCHEMBL3749579 | 0.75 | OPRK1 (0.59) | OPRK1OPRM1OPRD1BCHETAAR1 | |
| SCHEMBL16712746 | 0.75 | PYCR1 (0.35) | OPRK1OPRM1MEN1KMT2AHTR1A | |
| SCHEMBL20511000 | 0.75 | PYCR1 (0.35) | OPRK1OPRM1MEN1KMT2AHTR1A | |
| Bromide SCHEMBL10656516 | 0.74 | OPRK1 (0.57) | OPRK1OPRM1OPRD1BCHETAAR1 | |
| Hydrochloric Acid SCHEMBL2831864 | 0.74 | OPRK1 (0.60) | OPRK1OPRM1OPRD1BCHETAAR1 | |
| SCHEMBL4164073 | 0.73 | ALDH1A1 (0.47) | IGF1RMEN1KMT2ACNR2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009006-A1 | 3A,6-BRIDGED HEXAHYDROISOINDOLES AND RELATED HYDROISOQUINOLINES AND HYDROBENZAZEPINES AND THEIR USE AS RADIOIMAGING AND PHARMACEUTICAL AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-04-28 | — | — | WO | disclosed |